Research

Pipeline for Usher Syndrome Research (PUSH)

The Pipeline for Usher Syndrome Research (PUSH) at Boston Children’s Hospital will bring together six world-class scientists dedicated to accelerating the development of treatments for Usher Syndrome (USH). PUSH aims to tackle multiple forms of Usher Syndrome in parallel, identifying subtypes and mutations that may be amenable to innovative therapies. By advancing potential therapies over the next three years, PUSH will strive to identify optimized strategies that can move toward clinical trials, ultimately improving treatment options for hearing and vision loss associated with USH.

OUR WORLD CLASS SCIENTISTS LEADING PUSH RESEARCH

While there are several labs pursuing USH therapies around the world, here we have a unique opportunity because the six investigators are all leaders in their fields, are all located in one academic institution, and they all possess complementary expertise.

Why Your Support Matters:

Your donations will be crucial to launching this groundbreaking program. By supporting PUSH, you will:

  • Help identify treatable forms of USH and advance targeted therapies.

     

  • Support the development of various therapeutic approaches, such as gene replacement, antisense oligonucleotides (ASOs), genome editing, small molecules, and others.

     

  • Propel research toward clinical trials that could one day restore hearing and vision for those affected by USH.
A scientist is wearing a lab coat and is working with a test tube in his lab.